Cyber Police ESWAT sees the player as Duke Oda, a police officer accepted into the crime-ridden Liberty City Police Department's top unit, E.S.W.A.T. (Enhanced Special Weapons and Tactics). Duke starts off as a regular human being, but during the course of the game is given a powered exoskeleton to fight against a powerful high-tech crime organisation named "E.Y.E." which is threatening the city. His ultimate goal is to apprehend "Balzar" a mad scientist, when E.Y.E is revealed to be a rogue artificial intelligence computer.
ESWAT is a run-and-gun game in which the player must eliminate threats approaching from either side of the screen. After completing a few missions, player is accepted to the elite E.S.W.A.T. unit and given a power suit and special weapons. Each stage is divided to several levels, and a boss is waiting at the end of each stage.
Bullets: Increase the number of bullets player has.
Plasma Cannon: Powerful energy weapon that penetrates through enemies in a straight line.
Multi-Shot: Opens fire to all targets in front of the player in a 90 degrees angle.
Heat Charges: Launches two powerful bombs that travel around the screen. Strongest weapon in the game.
Cyber Police ESWAT's moderate success saw it ported to multiple platforms. Sega brought it to the Sega Master System in 1990, and U.S. Gold were given the license to publish versions for home computers, including the Amiga, Amstrad CPC, Atari ST, Commodore 64 and ZX Spectrum.
A "sequel" or "remake" in the form of ESWAT: City Under Siege was released for the Sega Mega Drive in 1990. Cyber Police ESWAT and ESWAT: City Under Siege are frequently mistaken to be the same game, but although both share a similar gameplay style, the Mega Drive game is very different.