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Sega Ages 2500 Series Vol. 14: Alien Syndrome (SEGA AGES 2500シリーズ Vol.14 エイリアンシンドローム) is the fourteenth entry in the Sega Ages 2500 series for the PlayStation 2.
Alien Syndrome acts as a re-imagining of the 1987 arcade release of Alien Syndrome, with much darker visuals presented entirely in 3D. Though it is a slower game, the player can take more than one hit and can fire in any direction using the right analogue stick (similar to Robotron 2084 or Smash T.V.). You can also rapid-fire in a single direction while moving in any direction.